| 摘要 |
The invention concerns heparanase inhibiting compounds of general formula (I) wherein R represents a hydrogen atom, an hydroxyl radical, a -OSO<SUB>3</SUB><SUP>-</SUP> radical, a -O-(C<SUB>1</SUB>-C<SUB>5</SUB>)alkyl radical or an -O- aralkyl radical; Z represents a COO<SUP>-</SUP> radical or a hydroxyl radical; X represents -OH or a saccharide unit of formula A, Y represents H, C<SUB>1</SUB>-C<SUB>5 </SUB>alkyl or a saccharide unit of formula D; in free form or in the form of pharmaceutically acceptable salts formed with a base or an acid as well as in the form of solvates or hydrates. The derivatives of the invention are useful as medicines. |
