发明名称 |
SCREENING METHOD FOR PROLINE-RICH PROTEINS |
摘要 |
A method for screening a pathogenic microorganism for a secreted or cellsurface protein potentially useful as a vaccine antigen involves the step of identifying proline-rich proteins, either as the amino acid level, or preferably at the DNA level by employing PCR. Suitable consensus sequences are described as (PXm)nP or (PPXq)nPP wherein: P is proline; X is any amino acid, m is from 1 to 5; q is 1 or 2; and n is 2 or more.
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申请公布号 |
CA2285480(A1) |
申请公布日期 |
1998.10.01 |
申请号 |
CA19982285480 |
申请日期 |
1998.03.24 |
申请人 |
CHIRON S.P.A. |
发明人 |
ARICO, BEATRICE;GRANDI, GUIDO;MASIGNANI, VEGA;RAPPUOLI, RINO |
分类号 |
G01N33/68;A61K31/711;A61K38/00;A61K39/106;A61P1/04;A61P31/04;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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