发明名称 Method of evaluating breast cancer, breast cancer-evaluating apparatus, breast cancer-evaluating method, breast cancer-evaluating system, breast cancer-evaluating program and recording medium
摘要 According to the method of evaluating breast cancer of the present invention, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be evaluated is measured, and a breast cancer state in the subject is evaluated based on the concentration value of at least one of Ser, Gln, Val, Cys, Orn, Arg, Ile and ABA contained in the measured amino acid concentration data of the subject.
申请公布号 US9459255(B2) 申请公布日期 2016.10.04
申请号 US200912487013 申请日期 2009.06.18
申请人 Ajinomoto Co., Inc. 发明人 Imaizumi Akira;Ando Toshihiko;Okamoto Naoyuki
分类号 G01N33/48;G01N33/574 主分类号 G01N33/48
代理机构 Foley & Lardner LLP 代理人 Foley & Lardner LLP
主权项 1. A method of evaluating breast cancer, comprising: a concentration value criterion evaluating step of evaluating, by a central processing unit (CPU) executing a breast cancer-evaluating program stored on a computer-readable recording medium, a breast cancer state in a subject to be evaluated, using at least concentration values of total Trp and at least one of Ser, Gln, Val, Cys, Orn, Arg, Ile, ABA, Ala, Asn, Cit, Glu, Gly, His, Leu, Lys, Met, Phe, Pro, Tau, Thr, and Tyr contained in amino acid concentration data on the concentration values of the amino acids in blood in the subject; wherein the concentration value criterion evaluating step further includes: a discriminant value calculating step of calculating, by the CPU, a discriminant value that is a value of a multivariate discriminant, using at least both the concentration values of total Trp and at least one of Ser, Gln, Val, Cys, Orn, Arg, Ile, ABA, Ala, Asn, Cit, Glu, Gly, His, Leu, Lys, Met, Phe, Pro, Tau, Thr, and Tyr contained in the amino acid concentration data of the subject and the multivariate discriminant for evaluating the breast cancer state containing total Trp and at least one of Ser, Gln, Val, Cys, Orn, Arg, Ile, ABA, Ala, Asn, Cit, Glu, Gly, His, Leu, Lys, Met, Phe, Pro, Tau, Thr, and Tyr as explanatory variables.
地址 Tokyo JP