PRODUCTION OF PURE LACTAM OF ENANTIOMER

摘要

Prodn. of enantiomeric lactams of formula (I) comprises reacting a racemate (I) with a biocatalyst which reacts with one enantiomer and isolating the unreacted enantiomer from the mixt. obtd. R1, R2 = 1-4C alkyl, 2-4C alkenyl or aryl (all opt. substd.), H or (CH2)n-COOH; n = 0-3; x = 1-5. Pref. the biocatalyst is a microorganism, esp. from Pseudomonas or Rhodococcus.