| 发明名称 |
CATHEPSIN K INHIBITION PROCESS |
| 摘要 |
<p>A novel cathepsin K crystalline stucture is identified. Also disclosed are methods of identifying inhibitors of this protease and methods of inhibiting cathepsin K using inhibitors with certain structural, physical and spatial characteristics.</p> |
| 申请公布号 |
CZ9702060(A3) |
申请公布日期 |
1999.02.17 |
| 申请号 |
CZ19970002060 |
申请日期 |
1996.10.30 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
ABDEL-MEQUID SHERIN SALAHELDIN;CARR THOMAS JOSEPH;DESJARLAIS RENEE LOUISE;GALLAGHER TIMOTHY FRANCIS;HALBERT STACIE MARIE;JANSON CHERYL ANN;MARQUIS ROBERT WELLS JR.;OH HYE-JA;RU YU;SMITH WARD WHITLOCK JR.;THOMPSON SCOTT KEVIN;VEBER DANIEL FRANK;YAMASHITA DENNIS SHINJI;YEN JACK HWEKWO;ZHAO BAOGUANG |
| 分类号 |
A61K31/16;A61K38/55;A61K45/00;A61P19/10;A61P43/00;C07C243/34;C07C311/16;C07C311/29;C07D207/26;C07D207/273;C07D211/72;C07D211/96;C07D213/30;C07D215/36;C07D241/24;C07D249/10;C07D271/10;C07D277/56;C07D285/12;C07D285/125;C07D295/155;C07D295/215;C07D307/91;C07D333/34;C07D333/76;C07D401/10;C07D401/12;C07D401/14;C07D405/12;C07D417/12;C07K5/06;C12N9/64;C12N9/99;C12Q1/37;G01N33/573;(IPC1-7):A61K31/16;A61K38/05;A61K31/425;A61K31/415;A61K31/165;C12N9/48 |
主分类号 |
A61K31/16 |
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