| 摘要 |
The invention relates to the compounds of formula I or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, and methods for the treatment of asthma and allergy may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of respiratory diseases, respiratory disorders, COPD, bronchitis, brain injury, inflammation, inflammatory skin diseases, asthma, allergic reactions, infections due to acute allergy, bronchospasm, respiratory distress, acute asthma, leukotrienes over activity, 5-LO enzyme activity and cancer. |
| 主权项 |
1. A compound of Formula I:or a pharmaceutically acceptable salt, hydrate, solvate, enantiomer, or stereoisomer thereof, wherein:
R1 represents R2 represents a is 2, 3 or 7; each b is independently 3, 5 or 6; e is 1, 2 or 6; c and d are each independently H, D, —OH, —OD, C1-C6-alkyl, —NH2 or —COCH3; and n is 1, 2, 3, 4 or 5. |
