发明名称 |
METHODS AND COMPOSITIONS FOR DIAGNOSIS OF INFLAMMATORY LIVER DISEASE |
摘要 |
The present disclosure provides methods and compositions that find use in facilitating a diagnosis of inflammatory liver disease in a subject. The methods and compositions generally involve detection of eotaxin-3 (E3) levels, either alone or with levels of eotaxin-1 (E1), and optionally, with levels of CCL22 and, further optionally, with levels of IL15. These levels can be used to facilitate a diagnosis of a liver disease of at least one of autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), and primary sclerosing cholangitis (PSC), and/or to facilitate a differential diagnosis between AIH, PBC, and PSC. The methods and compositions of the present disclosure also find use in facilitating treatment decisions for a subject. |
申请公布号 |
EP2893343(A4) |
申请公布日期 |
2016.08.31 |
申请号 |
EP20130835859 |
申请日期 |
2013.09.06 |
申请人 |
THE GOVERNORS OF THE UNIVERSITY OF ALBERTA;MEDIZINISCHE HOCHSCHULE HANNOVER |
发明人 |
LANDI, ABDOLAMIR;HOUGHTON, MICHAEL;TYRRELL, LORNE, D.;LANKISCH, TIM;WEISMUELLER, TOBIAS;MANNS, MICHAEL |
分类号 |
G01N33/48;G06F19/00 |
主分类号 |
G01N33/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|