发明名称 COMBINED AGENT FOR CELL THERAPY OF CORNEAL ENDOTHELIAL CELL
摘要 The present invention provides an agent for treating or preventing a disease, a disorder or a condition of a corneal endothelium, said agent comprising a corneal endothelial cell and a myosin II-specific inhibitor. More specifically, the myosin II-specific inhibitor is blebbistatin. The disease, the disorder or the condition is typically a disorder associated with Fuchs endothelial corneal dystrophy or corneal endothelial dysfunction (bullous keratopathy). Also provided is a method for treating or preventing a corneal endothelial disease, said method comprising a step of administering an effective amount of a myosin II-specific inhibitor together with a corneal endothelial cell to a subject.
申请公布号 US2016317528(A1) 申请公布日期 2016.11.03
申请号 US201315108355 申请日期 2013.12.27
申请人 KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION ;THE DOSHISHA ;SENJU PHARMACEUTICAL CO., LTD. 发明人 KOIZUMI Noriko;OKUMURA Naoki;KINOSHITA Shigeru
分类号 A61K31/4745;A61K9/00;A61K35/44;A61K35/30 主分类号 A61K31/4745
代理机构 代理人
主权项 1. (canceled)
地址 Kyoto-shi JP