发明名称 |
COMBINED AGENT FOR CELL THERAPY OF CORNEAL ENDOTHELIAL CELL |
摘要 |
The present invention provides an agent for treating or preventing a disease, a disorder or a condition of a corneal endothelium, said agent comprising a corneal endothelial cell and a myosin II-specific inhibitor. More specifically, the myosin II-specific inhibitor is blebbistatin. The disease, the disorder or the condition is typically a disorder associated with Fuchs endothelial corneal dystrophy or corneal endothelial dysfunction (bullous keratopathy). Also provided is a method for treating or preventing a corneal endothelial disease, said method comprising a step of administering an effective amount of a myosin II-specific inhibitor together with a corneal endothelial cell to a subject. |
申请公布号 |
US2016317528(A1) |
申请公布日期 |
2016.11.03 |
申请号 |
US201315108355 |
申请日期 |
2013.12.27 |
申请人 |
KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION ;THE DOSHISHA ;SENJU PHARMACEUTICAL CO., LTD. |
发明人 |
KOIZUMI Noriko;OKUMURA Naoki;KINOSHITA Shigeru |
分类号 |
A61K31/4745;A61K9/00;A61K35/44;A61K35/30 |
主分类号 |
A61K31/4745 |
代理机构 |
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代理人 |
|
主权项 |
1. (canceled) |
地址 |
Kyoto-shi JP |