CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS

摘要

Provided are certain chemical entities, and methods of use to modulate sk eletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, sk eletal troponin I, skeletal troponin T, and skeletal muscle, including fragm ents and isoforms thereof, as well as the skeletal sarcomere, and methods of use in the treatment of obesity, sarcopenia, wasting syndrome, frailty, cac hexia, muscle spasm, post-surgical and post-traumatic muscle weakness, neuro muscular disease, and other indications.