DOPAMINE RECEPTOR SUBTYPE LIGANDS

摘要

Fused tricyclic heteroaromatic compounds of formula (I) wherein one of X and Y represents nitrogen, and the other of X and Y represents oxygen, sulphur or N-R<2>; Q represents a substituted five- or six- membered monocyclic heteroaliphatic ring which contains one nitrogen atom as the sole heteroatom and is linked to the five-membered heteroatomic ring containing the moieties X and Y via a carbon atom as well as substituted 3,4-dihydro-1-hydroxy-2-oxomethyl-naphthalene precursors thereto, are ligands for dopamine receptor subtypes within the body and are therefore useful in the treatment of disorders of the dopamine system, in particular schizophrenia.