| 发明名称 |
TREATMENT OF AN INTESTINAL ADENOMA AND/OR ADENOCARCINOMA BY INHIBITION OF NOTCH PATHWAY ACTIVATION |
| 摘要 |
<p>The invention relates to the field of biochemistry and medicine. More specifically the invention relates to methods and pharmaceuticals for the treatment of intestinal neoplasia. The invention discloses the surprising finding that inhibitors of Notch pathway activation (for example gamma-secretase inhibitors) are extremely useful in the treatment of intestinal adenoma and/or adenocarcinoma.</p> |
| 申请公布号 |
EP1824503(A1) |
申请公布日期 |
2007.08.29 |
| 申请号 |
EP20050810788 |
申请日期 |
2005.11.10 |
| 申请人 |
HUBRECHT LABORATORIUM |
发明人 |
CLEVERS, JOHANNES CAROLUS;VAN GIJN, MARIA, ELISABETH;VAN ES, JOHANNES, HENDRIKUS |
| 分类号 |
A61K38/17;A61K38/55;A61P35/00 |
主分类号 |
A61K38/17 |
| 代理机构 |
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