| 主权项 |
1. A method of screening biochemical reactions induced in a cell by treatment with a test compound, the method comprising:
selecting two or more biochemical reactions for a test compound from known biochemical reactions by comparing one or more functional regions of the compound with one or more functional regions in a transformation library; identifying a set of genes, proteins, or metabolites differentially expressed in a cell in response to contacting the cell with the test compound; selecting one or more biological pathways known to be associated with the set of differentially expressed genes, proteins, or metabolites from known biological pathways; and determining the biochemical reaction included in the selected biological pathway, among the selected biochemical reactions, as a biochemical reaction induced in the cell by treatment with the test compound, wherein each of the steps are performed by at least one processor. |
