发明名称 Crystal
摘要 The present invention relates to a crystal. In particular the present invention relates to a crystal of the N-domain of ACE protein. The present invention also relates to methods, processes, domain specific modulators, pharmaceutical compositions and uses of the N-domain crystal and the structure co-ordinates thereof.
申请公布号 US9434933(B2) 申请公布日期 2016.09.06
申请号 US201414297500 申请日期 2014.06.05
申请人 ANGIODESIGN (UK) LTD. 发明人 Acharya Ravi;Sturrock Edward
分类号 C12N9/48;C07K14/705;A61K38/00 主分类号 C12N9/48
代理机构 Marshall, Gerstein & Borun LLP 代理人 Marshall, Gerstein & Borun LLP
主权项 1. A crystal of an N-Domain of ACE protein wherein the crystal belongs to the space group C2221, or wherein the crystal has the unit cell dimensions: a=101.12 Å, b=211.32 Å, c=171.27 Å, where in the N-domain consists of amino acids 1-629 of SEQ ID NO: 4.
地址 Wiltshire GB