发明名称 |
Crystal |
摘要 |
The present invention relates to a crystal. In particular the present invention relates to a crystal of the N-domain of ACE protein. The present invention also relates to methods, processes, domain specific modulators, pharmaceutical compositions and uses of the N-domain crystal and the structure co-ordinates thereof. |
申请公布号 |
US9434933(B2) |
申请公布日期 |
2016.09.06 |
申请号 |
US201414297500 |
申请日期 |
2014.06.05 |
申请人 |
ANGIODESIGN (UK) LTD. |
发明人 |
Acharya Ravi;Sturrock Edward |
分类号 |
C12N9/48;C07K14/705;A61K38/00 |
主分类号 |
C12N9/48 |
代理机构 |
Marshall, Gerstein & Borun LLP |
代理人 |
Marshall, Gerstein & Borun LLP |
主权项 |
1. A crystal of an N-Domain of ACE protein wherein the crystal belongs to the space group C2221, or wherein the crystal has the unit cell dimensions: a=101.12 Å, b=211.32 Å, c=171.27 Å, where in the N-domain consists of amino acids 1-629 of SEQ ID NO: 4. |
地址 |
Wiltshire GB |