INSULIN SECRETION PROMOTING AGENTS

摘要

The present disclosure relates to novel compounds, compositions containing same and methods for treating or preventing a condition associated with a deficient insulin secretion such as diabetes and metabolic syndrome in a subject in need thereof.

主权项

1. A compound of formula Ior a pharmaceutically acceptable salt or solvate thereof, wherein
X is N or CH; R1 is lower linear or branched alkyl, cycloalkyl, lower linear or branched alkenyl, cycloalkenyl or aryl; each of R2, R3, R4 and R5 is H or one or more independently selected substituent; R6 is H, lower linear or branched alkyl, or cycloalkyl; each of R7 and R8 is independently selected from H, lower alkyl or fluoride;provided that said compound is other than compounds i), ii) iii) and iv))