Integrity and Functionality Test for Adsorptive Depth Filter Layers with an Inorganic Layered Double Hydroxide

摘要

The present invention relates to a method for determining the functionality and integrity of depth filter sheets and depth filter sheet systems comprising inorganic layered double hydroxide for contaminant removal in biotechnological processes.

主权项

1. A method for determining the integrity and functionality of depth filter sheets and depth filter sheet systems comprising inorganic layered double hydroxides, comprising the steps of
loading the depth filter sheet comprising inorganic layered double hydroxide with an adsorbate, comprising inorganic anions, under conditions under with the adsorbate is completely retrained by the adsorptive depth filter sheet until the breakthrough volume is reached, detecting the broken-through adsorbate by means of a secondary reaction, the negative common logarithm of the detected limit concentration pD being ≧4, and comparing the breakthrough characteristics with those of an adsorptive depth filter sheet of known integrity.