| 发明名称 | Method for producing vaccinal viral strain of a virus of the <i>Reoviridae </i>family | ||
| 摘要 | The invention relates to a method for producing a modified viral strain of a virus which is a member of the Reoviridae family and, in particular, relates to vaccinal viral strains of the Orbivirus genus. | ||
| 申请公布号 | US9457076(B2) | 申请公布日期 | 2016.10.04 |
| 申请号 | US201414166675 | 申请日期 | 2014.01.28 |
| 申请人 | London School of Hygiene and Tropical Medicine | 发明人 | Roy Polly;Boyce Mark |
| 分类号 | A61K39/15;C12N7/00;C12N15/86;A61K39/12;A61K39/00 | 主分类号 | A61K39/15 |
| 代理机构 | Klarquist Sparkman, LLP | 代理人 | Klarquist Sparkman, LLP |
| 主权项 | 1. An isolated single stranded RNA (ssRNA) derived from the genome of a Bluetongue virus, wherein the ssRNA comprises a mutation which destroys the function of a Blue Tongue viral gene encoding a VP6 protein, wherein the mutation consists of a deletion of a deletion of nucleotides 301-743 of the gene encoding a Blue Tongue virus gene encoding the VP6 protein. | ||
| 地址 | London GB | ||