发明名称 |
Irinotecan hydrochloride composite phospholipid composition preparation method and use thereof |
摘要 |
An irinotecan hydrochloride composite phospholipid composition, preparation method and uses thereof in the preparation of drugs for treating tumors or drug resistant tumors. The composite phospholipid composition comprises irinotecan hydrochloride, composite phospholipid, cholesterol, long-circulating membrane material, surfactant and a buffer medium. The composition improves stability of lipid formulation and the anti-tumor effect of irinotecan hydrochloride, and can overcome multidrug resistance of a tumor. |
申请公布号 |
GB2538683(A) |
申请公布日期 |
2016.11.23 |
申请号 |
GB20160016625 |
申请日期 |
2015.03.06 |
申请人 |
Shanghai Institute of Materia Medica, Chinese Academy of Sciences;Shanghai Jingfeng Pharmaceutical Co., Ltd |
发明人 |
Yaping Li;Lingli Chen;Zhaolei Zheng;Zhiwen Zhang;Wangwen Gu |
分类号 |
A61K31/4745;A61K9/127;A61K47/04;A61P35/00 |
主分类号 |
A61K31/4745 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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