PROCESS FOR PRODUCING OPTICALLY ACTIVE 2-ALKOXYCYCLOHEXANOL DERIVATIVES

摘要

A process for efficiently producing (S,S)-2-alkoxycyclohexanols in a single step by using (+/- )-trans-2-alkoxycyclohexanols which are inexpensive and can be easily obtained. The process comprises treating a (+/- )-trans-2-alkoxycyclohexanol with a hydrolase originating in a microorganism and being capable of esterifying stereospecifically the R-isomer in the presence of an acyl donor under such conditions that no hydrolysis occurs substantially to thereby give (S,S)-2-alkoxycyclohexanols and (R,R)-2-alkoxycyclohexanol carboxylate and then taking up the (S,S)-2-alkoxycyclohexanols.