发明名称 |
FÜR MENSCHLICHE ALPHA-1-ADRENERGE REZEPTOREN KODIERENDE DNS UND IHRE VERWENDUNG |
摘要 |
This invention provides an isolated nucleic acid, vectors, transformed mammalian cells and non-human transgenic animals that encode and express normal or mutant alpha 1B adrenergic receptor genes. This invention also provides a protein, antibody directed to the protein and pharmaceutical compounds related to alpha 1B adrenergic receptors. This invention provides nucleic acid probe, antisense oligonucleotide complementary to alpha 1B adrenergic receptor genes. This invention further provides methods for determining ligand binding, detecting expression, drug screening, and treatments for alleviating abnormalities associated with human alpha 1B adrenergic receptors. |
申请公布号 |
DE69333594(D1) |
申请公布日期 |
2004.09.23 |
申请号 |
DE1993633594 |
申请日期 |
1993.09.24 |
申请人 |
SYNAPTIC PHARMACEUTICAL CORP., PARAMUS |
发明人 |
BARD, A.;FORRAY, CARLOS;WEINSHANK, L. |
分类号 |
A01K67/027;A61K38/00;A61K39/395;A61K45/00;A61P3/08;A61P9/06;A61P9/08;A61P9/10;A61P9/12;A61P13/02;A61P15/00;A61P27/02;A61P27/16;A61P43/00;C07H21/04;C07K14/705;C07K14/72;C07K16/28;C12N5/06;C12N15/09;C12N15/12;C12N15/85;C12P21/02;C12P21/08;C12Q1/02;C12Q1/68;G01N33/53;G01N33/577;G01N33/94 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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