发明名称 |
CROSSLINKER, Fcγ RECEPTOR EXPRESSION CELL ACCUMULATION AGENT, MOLECULE TARGET IMMUNOTHERAPY AGENT, LABELING REAGENT, Fcγ RECEPTOR EXPRESSION CELL ACCUMULATION METHOD, AND MOLECULE-TARGETED IMMUNOTHERAPY |
摘要 |
PROBLEM TO BE SOLVED: To provide a compound which can induce ADCC activity and CDC activity as is the same case with antibody preparations without using antibody preparations.SOLUTION: A crosslinker has a target recognition part (A) which recognizes a target molecule and a Fc recognition part (B) which recognizes the Fc region of an immunoglobulin, wherein the target recognition part (A) and the Fc recognition part (B) are bond. An Fcγ receptor expression cell accumulation agent and a molecule target immunotherapy agent contain the crosslinker. A labeling reagent contains the crosslinker which has further a marker substance (D). An Fcγ receptor expression cell accumulation method and a molecule-targeted immunotherapy are characterized by using the crosslinker.SELECTED DRAWING: None |
申请公布号 |
JP2016088906(A) |
申请公布日期 |
2016.05.23 |
申请号 |
JP20140227176 |
申请日期 |
2014.11.07 |
申请人 |
KYUSHU UNIV |
发明人 |
KATAYAMA YOSHIKI;MORI TAKESHI;FUNAMOTO DAIKI |
分类号 |
C07K5/12;A61K38/00;A61P31/04;A61P31/12;A61P35/00 |
主分类号 |
C07K5/12 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|