Orally administered corticosteroid compositions

摘要

The present invention is directed to orally administered corticosteroid compositions. The present invention also provides a method for treating a condition associated with inflammation of the gastrointestinal tract in an individual. The method comprises administering to an individual in need thereof a pharmaceutical composition of the present invention.

主权项

1. An oral, substantially non-aqueous liquid pharmaceutical composition comprising a corticosteroid, a pharmaceutically acceptable non-aqueous liquid, and a phase change agent dissolved or suspended in the non-aqueous liquid, wherein after oral administration to a patient, said composition undergoes a change in physical properties of the composition upon contact with the upper gastrointestinal tract of said patient, whereby contact of the corticosteroid with the upper gastrointestinal tract of the patient is enhanced and/or prolonged.