发明名称 Substituted Amino-Pyrimidones and Uses Thereof
摘要 This invention relates to novel compounds having the structural formula Ia or formula Ib below: (Ia, Ib), and their pharmaceutically acceptable salts, tautomers or in vivo hydrolysable precursors, compositions and methods of use thereof. These novel compounds provide a treatment or prophylaxis of Abeta related pathologies such as cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.
申请公布号 US2009062282(A1) 申请公布日期 2009.03.05
申请号 US20050577154 申请日期 2005.10.14
申请人 ASTRAZENECA AB 发明人 ALBERT JEFFREY SCOTT;ANDISIK DON;ARNOLD JAMES;BROWN DEAN;CALLAGHAN OWEN;CAMPBELL JAMES;CARR ROBIN ARTHUR ELLIS;CHESSARI GIANNI;CONGREVE MILES STUART;EDWARDS PHIL;EMPFIELD JAMES R.;FREDERICKSON MARTYN;KOETHER GERARD M.;KRUMRINE JENNIFER;MAUGER RUSS;MURRAY CHRISTOPHER WILLIAM;PATEL SAHIL;SYLVESTER MARK;THRONER SCOTT
分类号 A61K31/5377;A61K31/513;A61P25/28;C07D239/22;C07D413/10;C12N9/99 主分类号 A61K31/5377
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