发明名称 TREATMENT OR PROPHYLAXIS OF PROSTATIC CANCER AND BENIGN PROSTATIC HYPERPLASIA WITH SELECTIVE ESTROGEN RECEPTOR MODULATORS
摘要 The present invention provides a method for the treatment or prophylaxis of benign prostatic hyperplasia or prostatic cancer in a patient in need of such treatment comprising administering a selective estrogen receptor modulating compound of formula (I), in which R1 and R2 are independently hydroxy and alkoxy of one to four carbon atoms; and R3 and R4 are independently methyl or ethyl, or R3 and R4, taken together with the nitrogen atom to which they are attached, form a pyrrolidino, methyl-pyrrolidino, dimethylpyrrolidino, piperidino, morpholino, or hexamethyleneimino ring.
申请公布号 CA2286204(A1) 申请公布日期 1998.10.15
申请号 CA19982286204 申请日期 1998.04.07
申请人 ELI LILLY AND COMPANY 发明人 NEUBAUER, BLAKE LEE
分类号 C07D333/64;A61K31/381;A61K31/4025;A61K31/4535;A61K31/5377;A61K31/55;A61P5/30;A61P13/00;A61P35/00;A61P43/00;(IPC1-7):C07D409/12;A61K31/38;A61K31/535 主分类号 C07D333/64
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