发明名称 |
TRANSDUCTIN-1 AND TRANSDUCTIN-2 AND APPLICATIONS TO HEREDITARY DEAFNESS |
摘要 |
The invention provides an isolated or purified nucleic acid molecules consisting essentially of the nucleotide sequence encoding either transductin-1 (TDC1) or transductin-2 (TDC2), related and derivative nucleic acid molecules vectors comprising the isolated or purified nucleic acid sequences, cells comprising such vectors, polypeptides encoded by the nucleic acid molecules, monoclonal antibodies and cell lines producing the monoclonal antibodies. The invention also provides methods of treating, prognosticating and monitoring hearing loss.
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申请公布号 |
US2007099271(A1) |
申请公布日期 |
2007.05.03 |
申请号 |
US20060615250 |
申请日期 |
2006.12.22 |
申请人 |
GOVERNMENT OF THE U.S.A., REPRESENTED BY THE SECRETARY, DEPT.OF HEALTH & HUMAN SERVICES |
发明人 |
GRIFFITH ANDREW J.;KURIMA KIYOTO;WILCOX EDWARD;FRIEDMAN THOMAS |
分类号 |
A61K48/00;G01N33/53;A61K31/7052;A61K35/12;A61K38/00;A61P27/16;C07H21/04;C07K14/47;C07K14/705;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/06;C12P21/08;C12Q1/68;G01N33/566 |
主分类号 |
A61K48/00 |
代理机构 |
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地址 |
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