发明名称 Low hygroscopic aripipazole drug substance and processes for the preparation thereof
摘要 The present invention provides low hygroscopic forms of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the aripiprazole anhydride crystals is stored for an extended period.
申请公布号 US2007202181(A1) 申请公布日期 2007.08.30
申请号 US20070790605 申请日期 2007.04.26
申请人 OTSUKA PHARMACEUTICAL CO., LTD. 发明人 BANDO TAKUJI;AOKI SATOSHI;KAWASAKI JUNICHI;ISHIGAMI MAKOTO;TANIGUCHI YOUICHI;YABUUCHI TSUYOSHI;FUJIMOTO KIYOSHI;NISHIOKA YOSHIHIRO;KOBAYASHI NORIYUKI;FUJIMURA TSUTOMU;TAKAHASHI MASANORI;ABE KAORU;NAKAGAWA TOMONORI;SHINHAMA KOICHI;UTSUMI NAOTO;TOMINAGA MICHIAKI;OOI YOSHIHIRO;YAMADA SHOHEI;TOMIKAWA KENJI
分类号 A61K9/14;C07D215/22;A61K;A61K9/16;A61K9/20;A61K31/4704;A61K31/496;A61K31/497;A61K31/501;A61P;A61P1/08;A61P3/04;A61P15/10;A61P25/00;A61P25/04;A61P25/16;A61P25/18;A61P25/22;A61P25/28;A61P25/32;B01D9/02;C07D;C07D215/227;C07D401/12 主分类号 A61K9/14
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