主权项 |
1. A method of treating, or minimizing the risk of, cardiovascular or cerebrovascular disease in a patient in need thereof, comprising administering to said patient an therapeutically effective amount of O-(4-dimethylaminoethoxycinnamoyl)fumagillol or pharmaceutically acceptable salts thereof thereby increasing serum levels of high density lipoproteins in said patient, wherein said therapeutically effective amount does not substantially modulate or suppress angiogenesis and wherein the patient is suffering from diabetes, thereby treating, or minimizing the risk of, cardiovascular or cerebrovascular disease in said patient. |