Immunogenic composition comprising atleast two N. meningitidis capsular polysaccharides conjugated through a linker protein

摘要

Disclosed is an immunogenic composition comprising at least 2 different N. meningitidis capsular saccharides, wherein one or more is/are selected from a first group consisting of MenA, MenC, MenY and MenW which is/are conjugated through a linker to a carrier protein, and one or more different saccharides is/are selected from a second group consisting of MenA, MenC, MenY and MenW which is/are directly conjugated to a carrier protein. Further disclosed is a vaccine and vaccine kit comprising said immunogenic compositions and processes for the manufacture and uses thereof.