| 发明名称 |
IMMUNOCYTOKINES WITH MODULATED SELECTIVITY |
| 摘要 |
The invention relates to IL-2 fusion protein with improved therapeutic characteristics, especially with reduced toxicity and / or immunogenicity by modification of the amino acid sequence of the IL-2 moiety. |
| 申请公布号 |
PL206975(B1) |
申请公布日期 |
2010.10.29 |
| 申请号 |
PL20020369741 |
申请日期 |
2002.12.04 |
| 申请人 |
MERCK PATENT GMBH |
发明人 |
GILLIES STEPHEN D. |
| 分类号 |
C12N15/62;C12Q1/02;A61K38/00;A61P35/00;A61P35/04;A61P37/02;C07K14/55;C07K16/18;C07K16/24;C07K19/00;G01N33/53;G01N33/566 |
主分类号 |
C12N15/62 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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