发明名称 |
Substituted cyclohexyl and piperidinyl derivatives as melanocortin-4 receptor modulators |
摘要 |
<p>The present invention relates to novel substituted cyclohexyl and piperidinyl derivatives as melanocortin-4 receptor (MC-4R) modulators. MC-4R agonists of the invention can be used for the treatment of disorders and diseases such as obesity, diabetes and sexual dysfunction, whereas the MC-4R antagonists are useful for the treatment of disorders and diseases such as cancer cachexia, muscle wasting, anorexia, anxiety and depression. All diseases and disorders where the regulation of the MC-4R is involved can be treated with the compounds of the invention.</p> |
申请公布号 |
EP1460069(A1) |
申请公布日期 |
2004.09.22 |
申请号 |
EP20030006255 |
申请日期 |
2003.03.20 |
申请人 |
SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH |
发明人 |
SOEBERDT, MICHAEL;WEYERMANN, PHILIPP;SPRECHER VON, ANDREAS |
分类号 |
A61K31/4725;A61P3/04;A61P15/00;A61P25/22;A61P25/24;C07D211/70;C07D217/26;C07D401/10;C07D401/12;C07D401/14;C07D405/12;C07D405/14;(IPC1-7):C07D401/10;A61K31/472 |
主分类号 |
A61K31/4725 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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