| 发明名称 |
SIALYLATED GLYCOPROTEINS |
| 摘要 |
Pharmaceutical preparations containing polypeptides having particular sialylation patterns, and methods for the treatment of immune-related thrombocytopenia with such preparations, are described. |
| 申请公布号 |
US2016257754(A1) |
申请公布日期 |
2016.09.08 |
| 申请号 |
US201415028917 |
申请日期 |
2014.10.14 |
| 申请人 |
MOMENTA PHARMACEUTICALS, INC. |
发明人 |
SCHULTES Birgit C.;CHU Chia Lin;RUTITZKY Laura;ZHANG Lynn;LING Leona E. |
| 分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutical preparation formulated for subcutaneous administration, said preparation comprising polypeptides comprising an Fc region, wherein at least 50% of branched glycans on the Fc region are di-sialylated by way of NeuAc-α 2,6-Gal terminal linkages. |
| 地址 |
Cambridge MA US |
