发明名称 |
Compositions and methods for treatment of hemorrhage |
摘要 |
Methods of treating hemorrhage are provided, comprising diagnosing one or more hemorrhaging or potentially hemorrhaging vessels in a patient and administering to the patient a therapeutically effective amount of a composition comprising a vessel closing compound at a concentration between about 0.1% and about 45%. The vessel closing compound may comprise a polymer with hydrophilic properties, such as polyethylene glycol (PEG). The composition may also comprise one or more active agent such as a blood flow modifier with a potential to form ionic bonds with the vessel closing agent. |
申请公布号 |
US9452183(B2) |
申请公布日期 |
2016.09.27 |
申请号 |
US201414511789 |
申请日期 |
2014.10.10 |
申请人 |
Warsaw Orthopedic, Inc. |
发明人 |
Roy Josee |
分类号 |
A61K33/06;A61K9/00;A61K31/74;A61K31/08;A61K31/77;A61K45/06;A61K47/10 |
主分类号 |
A61K33/06 |
代理机构 |
Sornell, Lenna & Schmidt LLP |
代理人 |
Sornell, Lenna & Schmidt LLP ;Schmidt, Esq. William D. |
主权项 |
1. A method of treating a hemorrhage comprising: diagnosing one or more hemorrhaging vessels in a patient; and administering to the patient a formulation of a vessel closing compound comprising polyethylene glycol (PEG) and an active agent comprising magnesium having a concentration of about 0.8% weight per volume of the formulation, wherein a dose of the formulation is administered within 30 to 90 minutes of a half-life of the PEG. |
地址 |
Warsaw IN US |