| 发明名称 | Amine derivative compounds for treating ophthalmic diseases and disorders | ||
| 摘要 | Provided are amine derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions. | ||
| 申请公布号 | US9452153(B2) | 申请公布日期 | 2016.09.27 |
| 申请号 | US201514720705 | 申请日期 | 2015.05.22 |
| 申请人 | ACUCELA INC. | 发明人 | Scott Ian L.;Kuksa Vladimir A.;Orme Mark W.;Hong Feng;Little, Jr. Thomas L.;Kubota Ryo |
| 分类号 | C07C213/00;A61K31/382;A61K31/138;A61K31/351;A61K31/165 | 主分类号 | C07C213/00 |
| 代理机构 | Wilson, Sonsini, Goodrich & Rosati | 代理人 | Wilson, Sonsini, Goodrich & Rosati |
| 主权项 | 1. A method for treating an ophthalmic disease or disorder resulting at least in part from lipofuscin pigment accumulated in a subject, comprising administering to the subject a compound, or a pharmaceutically acceptable salt, or N-oxide thereof, chosen from: | ||
| 地址 | Seattle WA US | ||