| 发明名称 |
METHODS FOR REDUCING ANXIETY AND IMPULSIVITY IN SUBJECTS INITIATING TREATMENT WITH SEROTONIN REUPTAKE INHIBITORS |
| 摘要 |
The present invention provides compositions and uses thereof for reducing anxiety and/or impulsivity, including, for example, suicidality, in a subject undergoing treatment with a serotonin reuptake inhibitor (SRI) comprising administering to the subject an effective amount of a SRI and an effective amount of a 5-HT1A receptor partial agonist/antagonist. In addition, the present invention provides dosing regimens for various SSRIs which can also reduce anxiety and/or impulsivity, including, for example, suicidality in a subject undergoing treatment with an SSRI. Kits including daily dosing regimens of various SSRIs are also provided. |
| 申请公布号 |
US2016375016(A1) |
申请公布日期 |
2016.12.29 |
| 申请号 |
US201414900636 |
申请日期 |
2014.06.24 |
| 申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
Kaplin Adam I.;Hendrix Craig W.;Rahn Kristen A. |
| 分类号 |
A61K31/496;A61K31/343;A61K31/381;A61K31/357;A61K31/137;A61K31/138;A61K31/135 |
主分类号 |
A61K31/496 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for reducing anxiety and/or impulsivity in a subject undergoing treatment with a serotonin reuptake inhibitor (SRI) comprising administering to the subject in need thereof, an effective amount of a SRI and an effective amount of a 5-HT1A receptor partial agonist/antagonist, and a pharmaceutically acceptable carrier. |
| 地址 |
Baltimore MD US |
