New pyrazolo(3,4-b)pyridin-3-yl)-5-pyrimidinyl sulfonates, are soluble guanyl cyclase stimulants useful e.g. for treating cardiovascular, thromboembolic or central nervous system diseases

摘要

4-Amino-(1-(2-fluorobenzyl)-1H-pyrazolo(3,4-b)pyridin-3-yl)-5-pyrimidinyl sulfonates (I) are new Pyrazolo-pyridines of formula (I) and their salts, isomers and hydrates are new. R<1> = -O-SO2R; R<3> = 1-6C alkyl, 3-8C cycloalkyl or phenyl (all optionally substituted); R<2> = H, optionally substituted (1-6C) alkylcarbonyl or optionally substituted 1-6C alkylsulfonyl. An Independent claim is included for the preparation of (I).