| 摘要 |
A compound of the formula (I): and isomers, salts, solvates, chemically protected forms, and prodrugs thereof, wherein: R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4 </SUP>and R<SUP>5 </SUP>are independently selected from the group consisting of H, C<SUB>1-7 </SUB>alkoxy, amino, halo or hydroxy; n is 1 or 2; R<SUP>N1 </SUP>and R<SUP>N2 </SUP>are independently selected from H and R, where R is optionally substituted C<SUB>1-10 </SUB>alkyl, C<SUB>3-20 </SUB>heterocyclyl and C<SUB>5-20 </SUB>aryl; or R<SUP>N1 </SUP>and R<SUP>N2</SUP>, together with the nitrogen atom to which they are attached form an optionally substituted 5-7 membered, nitrogen containing, heterocylic ring; Het is selected from: where Y<SUP>1 </SUP>and Y<SUP>3 </SUP>are independently selected from CH and N, Y<SUP>2 </SUP>is selected from CX and N and X is H, Cl or F; and where Q is O or S. |
