METHOD FOR RELATIVE QUANTITATION OF CHROMOSOMAL DNA COPY NUMBER IN A SINGLE OR FEW CELLS
摘要
The present invention is directed to methods for determining the presence or absence of a genetic defect in an IVF embryo prior to transfer comprising performing real-time PCR and 2-.DELTA..DELTA.C T analyses to determine normalized copy number of at least one invariant locus on at least one chromosome collected from at least one cell of the embryo and selecting a candidate IVF embryo determined to be without genetic defect for transfer.