发明名称 |
LIGHT-UP PROBES BASED ON FLUOROGENS WITH AGGREGATION INDUCED EMISSION CHARACTERISTICS FOR CELLULAR IMAGING AND DRUG SCREENING |
摘要 |
The present invention is drawn toward luminogens and chemical compositions comprising a target recognition motif, a hydrophilic moiety, a linking moiety, and at least one luminogen. Additionally presented are methods of: assessing the conversion of a prodrug into its active form, assessing the therapeutic efficacy of a prodrug, detecting glutathione in a biological sample, detecting alkaline phosphatase in a sample, and conducting fluorescence imaging or magnetic resonance imaging with the use of luminogen-containing compositions. |
申请公布号 |
SG11201606147S(A) |
申请公布日期 |
2016.08.30 |
申请号 |
SG11201606147S |
申请日期 |
2015.01.27 |
申请人 |
NATIONAL UNIVERSITY OF SINGAPORE;THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY |
发明人 |
LIU, BIN;SHAO, JINJUN;YUAN, YOUYONG;LIANG, JING;TANG, BENZHONG;SONG, ZHEGANG;CHEN, YILONG;KWOK, TSZ KIN |
分类号 |
G01N33/52;A61K31/28;A61K31/282;A61K31/4192;A61K31/44;A61K38/12;A61K103/34;C07D213/20;C07D213/24;C07F9/145;C07K7/64;C09K11/77;C09K11/87;G01N33/53 |
主分类号 |
G01N33/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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