FIBER OPTIC ANALYTE SENSOR WITH INTEGRATED IN SITU TOTAL PRESSURE CORRECTION

摘要

A fiber optic analyte sensing needle (10, 20) employing an analyte-partial-pressure-sensitive photoluminescent probe (70), characterized by (i) a void volume channel (68) extending axially along the length of the lumen (29) between the inner surface of the tube and the outer surface of the fiber optic filament (50), and (ii) a total pressure sensor (90) in pressure communication with the distal tip (20 2 ) of the needle (20) via the void volume channel (68), whereby total pressure of a volume sampled by the sensing needle (20) can be routinely measured and used in pressure compensation of analyte-concentration values calculated from the analyte-partial-pressure readings taken from the analyte-partial-pressure-sensitive photoluminescent probe (70).