Water soluble derivatives of cannabinoids

摘要

Water-soluble esters of tetrahydrocannabinoids, which are well-suited for administration in therapeutic aqueous formulations, having following general formula: <IMAGE> wherein a - - - b designates a 9(10) or a 9(8) double bond, R' is a -(CH2)n- linkage group where n is 1-8, and R is a -(CZ2)n- linkage group where n is 6 or more and Z independently is H or a substituent such as a lower alkyl group, and the pharmaceutically acceptable salts of these compounds.