| 摘要 |
Described are pharmaceutical compositions comprising polynucleotides encoding TGAP7 protein or a biologically fragment thereof. Furthemore, pharmaceutical compositions are described which comprise vectors comprising the aforementioned polynucleotides and/or host cells transformed therewith. Additionally, pharmaceutical compositions comprising antisense constructs to be aforementioned polynucleotides are described. Furthermore, methods and uses for modulating immune responses through the TGAP7 protein as well as pharmaceutical compositions comprising agents which act on the TGAP7 protein are described. Also, the use of said polynucleotide, vector, protein or antibody for the preparation of diagnostic and pharmaceutical compositions for use, inter alia, in organ transplantation, for the treatment of autoimmune, allergic or infectious diseases, or for treatment of tumors is provided. |
