发明名称 |
NIPAH VIRUS ENVELOPE PSEUDOTYPED LENTIVIRUSES AND METHODS OF THEIR USE |
摘要 |
The present invention relates to lentiviral particles which have been pseudotyped with Nipah virus (NiV) fusion (F) and attachment (G) glycoproteins (NiVpp-F/G). Additionally, the present invention relates to truncated NiV-F glycoproteins useful in producing such NiVpp lentiviral particles, as well as to additional variant peptides which enhance activity. Further, the present invention relates to methods of using such lentiviral particles or sequences, for example in the treatment of cancer or CNS disorders. |
申请公布号 |
EP2844746(A4) |
申请公布日期 |
2016.07.20 |
申请号 |
EP20130769106 |
申请日期 |
2013.03.15 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
LEE, BENHUR;PALOMARES, KARINA;PERNET, OLIVIER |
分类号 |
C12N7/01;A61K39/12;A61P35/00;C12N7/00;C12N15/86 |
主分类号 |
C12N7/01 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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