MEANS FOR DETECTING OR MEASURING A BIOLOGICAL ACTIVITY OF A BOTULINUM TOXIN

摘要

The present invention mainly relates to the field of the quality assessment of botulinum toxins for in vivo use, and especially for human use. The present invention notably relates to a method for in vitro detecting and/or measuring a biological activity of one or more botulinum toxin(s) by implementing one or more membrane vesicle(s), in particular exosomes, expressing at their surface one or more botulinum toxin receptor(s) selected in a group comprising SV2, synaptotagmin, and fragment(s) thereof.