发明名称 |
Stabil ikke-hygroskopisk krystallinsk form av N-[N-N-(4-(piperidin-4-yl)butanoyl)-N-etylglysyl]forbindelser |
摘要 |
<p>The invention is directed to a non-hygroscopic stable crystalline form of the antithrombotic compound N-[N-[N-(4-piperdin-4-yl)butanoyl)-N-ethylglycyl]-(L)-aspartyl]-(L)- beta -cyclohexyl-alanine amide, to processes for preparing said stable crystalline form, to a pharmaceutical composition thereof, and intermediates thereof, and the invention is directed also to processes for preparing a compound of the formula wherein: A, B, Z, E1, E2, G, R, m, n, and p are as defined herein.</p> |
申请公布号 |
NO990721(D0) |
申请公布日期 |
1999.02.16 |
申请号 |
NO19990000721 |
申请日期 |
1999.02.16 |
申请人 |
RHONE-POULENC RORER PHARMACEUTICALS INC |
发明人 |
CHRZAN, ZOFIA J.;MENCEL, JAMES J.;TOLEDO-VELASQUEZ, DAVID;WINDISCH, VINCENT;WOODWARD, RICK G.;SALAZAR, DIANE C.;VEMURI, NARASIMHA M.;GARDETTO, ANTHONY J.;POWERS, MATTHEW R.;KUBIAK, GREGORY G.;LIU, ROBERT C.;VANASSE, BENOIT J.;SHERBINE, JAMES P.;RODRIGUEZ, WALTER;SLEDESKI, ADAM W. |
分类号 |
C07D211/70;A61K38/00;A61P7/02;A61P9/10;C07D211/34;C07K5/02;C07K5/062;C07K5/083;(IPC1-7):C07D |
主分类号 |
C07D211/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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