发明名称 2-HETEROARYL-IMIDAZOTRIAZINONES AND THEIR USE IN THE TREATMENT OF INFLAMMATORY OR IMMUNE DISEASES
摘要 <p>The invention relates to 2-Heteroaryl-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases. The present invention relates to compounds of the general formula (I) in which R<SUP>1 </SUP>denotes 5- to 10-membered heteroaryl, which is optionally substituted by identical or different residues selected from the group consisting of halogen, (C<SUB>1</SUB>-C<SUB>4</SUB>)-alkyl, trifluoromthyl, cyano, nitro und trifluoromethoxy, denotes 3- to 10-membered carbocyclyl or carbon-bonded, 4- to 10-membered heterocyclyl, whereby carbocyclyl and heterocyclyl are optionally substituted by identical or different residues selected from the group consisting of (C<SUB>1</SUB>-C<SUB>6</SUB>)-aldyl, (C<SUB>1</SUB>-C<SUB>6</SUB>)-aldoxy, hydroxy, halogen, trifluoromethyl and oxo, or denotes (C<SUB>2</SUB>-C<SUB>10</SUB>)-alkyl, which is optionally substituted by identical or different residues selected from the group the group consisting of (C<SUB>1</SUB>-C<SUB>6</SUB>)-alkoxy, hydroxy, halogen, 3- to 10-membered carbocyclyl and oxo.</p>
申请公布号 EP1399439(B1) 申请公布日期 2006.06.14
申请号 EP20020730265 申请日期 2002.05.21
申请人 BAYER HEALTHCARE AG 发明人 ALONSO-ALIJA, CRISTINA;GIELEN, HEIKE;HENDRIX, MARTIN;NIEWOEHNER, ULRICH;SCHAUSS, DAGMAR;BISCHOFF, HILMAR;BURKHARDT, NILS;GEISS, VOLKER;SCHLEMMER, KARL-HEINZ;CUTHBERT,NIGEL;CUTHBERT, NIGEL;FITZGERALD, MARY.F.;STURTON, GRAHAM.;NIEWOEHNER, MARIA, THERESIA
分类号 C07D409/04;A61K31/53;A61P1/00;A61P1/04;A61P3/10;A61P7/00;A61P7/04;A61P9/00;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P11/08;A61P13/12;A61P17/00;A61P17/06;A61P19/02;A61P19/08;A61P21/00;A61P25/00;A61P25/24;A61P25/28;A61P27/14;A61P29/00;A61P31/04;A61P31/18;A61P33/06;A61P35/00;A61P37/00;A61P37/02;A61P37/06;A61P37/08;A61P39/00;A61P43/00;C07D401/04;C07D403/04;C07D405/04;C07D407/04;C07D417/04;C07D487/04 主分类号 C07D409/04
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