发明名称 COMPOSITIONS AND METHODS RELATING TO MANIPULATION OF THE MYELOID IMMUNE COMPARTMENT DURING RESPIRATORY INFECTION
摘要 The invention relates to therapeutic compositions for use in treating, ameliorating or preventing an infection such as a microbial infection in a subject, comprising a compound modulative of reactive oxygen species level, or CD200 level, or CD200R level, or a combination of two or more of said levels in said subject. The invention also relates to methods of treatment using such compositions. In addition, the invention relates to therapeutic compositions for use in treating, ameliorating or preventing an inflammatory pulmonary infection in a mammalian host having a CD200-CD200R axis comprising a compound modulative of said axis, and to methods of treatment using such compositions. Furthermore, the invention relates to therapeutic compositions for use in treating, ameliorating or preventing a microbial infection and/or pulmonary inflammation in a subject comprising a compound mimetic of superoxide dismutase, and to methods of treatment using such compositions.
申请公布号 WO2009004339(A2) 申请公布日期 2009.01.08
申请号 WO2008GB02280 申请日期 2008.07.03
申请人 IMPERIAL INNOVATIONS LIMITED;HUSSELL, TRACY;SNELLGROVE, ROBERT 发明人 HUSSELL, TRACY;SNELLGROVE, ROBERT
分类号 A61K31/409;A61P11/00;A61P31/00 主分类号 A61K31/409
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