发明名称 |
NON-POLYMERIC COMPOSITIONS FOR CONTROLLED DRUG DELIVERY |
摘要 |
The present invention provides a novel liquid composition suitable for in-situ formation of a depot system to deliver a bioactive substance in a controlled manner. The composition of the present invention comprises: (a) a hydrophobic non-polymeric carrier material; (b) a water miscible biocompatible organic solvent that dissolves the hydrophobic non-polymeric material; (c) an ionic complex that is formed between an amphiphilic molecule and a bioactive substance having a net charge at neutral pH in water. The present invention also provides a method of manufacturing and use of the composition thereof. |
申请公布号 |
CA2714514(C) |
申请公布日期 |
2016.08.16 |
申请号 |
CA20092714514 |
申请日期 |
2009.02.05 |
申请人 |
QPS LLC |
发明人 |
LI, YUHUA;GUARINO, ANDREW;CHIEN, BENJAMIN |
分类号 |
A61K47/26;A61K47/14;A61K47/20 |
主分类号 |
A61K47/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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