The invention relates to stem cells isolated from the retina of mammals and retinal cells differentiated from these stem cells. The invention also relates to a method of isolating retinal stem cells and inducing retinal stem cells to produce retinal cells. Retinal stem cells may also be induced in vivo to produce retinal cells. The invention also includes pharmaceuticals made with retinal stem cells or retinal cells which may be used to restore vision lost due to diseases, disorders or abnormal physical states of the retina. The invention includes retinal stem cell and retinal cell culture systems for toxicological assays, for isolating genes involved in retinal differentiation or for developing tumour cell lines.
申请公布号
CA2216439(A1)
申请公布日期
1998.03.25
申请号
CA19972216439
申请日期
1997.09.24
申请人
VAN DER KOOY, DEREK;TROPEPE, VINCENZO;CHIASSON, BERNARD;MCINNES, RODERICK
发明人
VAN DER KOOY, DEREK;TROPEPE, VINCENZO;CHIASSON, BERNARD;MCINNES, RODERICK