发明名称 |
MODIFIED <i>MORBILLIVIRUS</i> V PROTEINS |
摘要 |
Modified <i>Morbilliviruses</i> having at least one mutation in the region corresponding to amino acids 112-134 of the measles virus V protein are described wherein one or both of amino acids 113 or 114 is mutated. Such modified <i>Morbilliviruses</i> exhibit reduced repression of gene expression. Additional mutations or deletions in other regions of the genome may be included, including in the carboxy-terminal region. |
申请公布号 |
WO0200694(A2) |
申请公布日期 |
2002.01.03 |
申请号 |
WO2001US19806 |
申请日期 |
2001.06.21 |
申请人 |
AMERICAN CYANAMID COMPANY;PARKS, CHRISTOPHER, L. |
发明人 |
PARKS, CHRISTOPHER, L. |
分类号 |
C12N15/09;A61K39/155;A61K39/165;C07K14/12;C12N7/00;C12N7/02;C12N7/04 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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