发明名称 |
Fast Wet-Massing Method for the Preparation of Calcium-Containing Compositions |
摘要 |
The present invention relates to a novel process for the preparation of a granulate comprising a calcium-containing compound as an active substance. The method comprises a method for the preparation of a granulate comprising a calcium-containing compound as an active substance, the method comprising, i) feeding a granulation chamber with a composition comprising the calcium-containing compound, ii) wet-massing the composition with a granulation liquid optionally comprising a pharmaceutically acceptable binder for a time period of at the most 30 sec to obtain a wet granulate, iii) drying the thus obtained wet granulate. A granulate obtained by the present method is especially suitable in the preparation of solid dosage forms, in particular in the preparation of tablets.
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申请公布号 |
US2008317842(A1) |
申请公布日期 |
2008.12.25 |
申请号 |
US20060883536 |
申请日期 |
2006.02.02 |
申请人 |
BERTELSEN POUL E;OLSEN PEDER M;NIELSEN CARSTEN M;TOLLESHAUG MAGNUS W |
发明人 |
BERTELSEN POUL E.;OLSEN PEDER M.;NIELSEN CARSTEN M.;TOLLESHAUG MAGNUS W. |
分类号 |
A61K9/48;A61K9/20;A61K33/10;A61P19/08 |
主分类号 |
A61K9/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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