发明名称 Monoclonal antibody against necrosis marker ERP29 and use thereof
摘要 [PROBLEM] To provide a monoclonal antibody against a biomarker which shows high specificity and can be effectively used in detection and diagnosis of various lesions relevant to various kinds of carcinomas and foci of necrosis, and so forth.;[MEANS] A monoclonal antibody against a necrosis marker consisting the following amino acid sequence: (1) the amino acid sequence of any of SEQ ID NOs: 1 to 3, or (2) an amino acid sequence having substitution, deletion and/or insertion of one or several amino acid residues in the amino acid sequence of (1) or sharing a homology of 90% or more with the amino acid sequence of (1), and showing the same function, activity or property as that of the amino acid sequence of (1) as a protein.
申请公布号 US9377461(B2) 申请公布日期 2016.06.28
申请号 US201113583312 申请日期 2011.03.08
申请人 FUJIFILM Corporation 发明人 Sugano Sumio;Kanzaki Yukari;Saga Tsuneo;Tsuji Atsushi
分类号 C07K16/00;C12P21/08;G01N33/574;A61K51/10;C07K16/30;C07K16/18 主分类号 C07K16/00
代理机构 Sughrue Mion, PLLC 代理人 Sughrue Mion, PLLC
主权项 1. A monoclonal antibody, which is produced by a hybridoma having accession number NITE ABP-1063.
地址 Tokyo JP